Abhiraj P|May 25, 2022
IIT Roorkee develops nanobiotic platform to combat bacterial pathogens
IIT Roorkee researchers developed a technology platform, shown to have applications in the health sector and food packaging.
NEW DELHI: The Indian Institute of Technology Roorkee (IIT Roorkee) researchers have developed a multimodal nanobiotic platform which combats bacterial pathogens. The nanoplatform leverages the synergistic antibacterial activity of a food-grade peptide to mitigate multidrug-resistant bacterial pathogens. The technology platform has been shown to have applications in the health sector and food packaging.
“The team used pediocin; a class IIa bacteriocin to decorate silver (Ag°)nanoparticles and developed a double-edged nano-platform (Pd-SNPs) that inherits intrinsic properties of both antibacterial moieties, which engenders strikingly high antibacterial potency against a broad spectrum of bacterial pathogens including the ESKAPE category (six antibiotic-resistant bacterial pathogens) without displaying adverse cytotoxicityto mammalian cells,” said an official statement from the IIT Roorkee.
The research team that contributed to the study from IIT Roorkee are Professor Naveen Kumar Navani, Chemical Biology Laboratory, Department of Biosciences and Bioengineering and Adjunct Faculty, Centre of Nanotechnology; Piyush Kumar, Arshad Ali Shaikh, Pardeep Kumar, Rajat Dhyani, Tarun Kumar Sharma,Ajmal Hussain, Chemical Biology Laboratory, Department of Biosciences and Bioengineering; Vivek Kumar Gupta, Ranjana Pathania, Molecular Bacteriology and Chemical Genetics Laboratory, Department of Biosciences and Bioengineering;KrishnakantGangele, Krishana Mohan Poluri, Mechanistic Biological Chemistry Laboratory, Department of Biosciences and Bioengineering.
Professor Ajit K Chaturvedi, Director, IIT Roorkee, said, “I would like to congratulate the research team at IIT Roorkee for their novel idea towards developing a vehicle to mitigate persistant bacterial infections. This will open up new avenues for combating a wide range of pathogens in the health or food sector.”
To get in touch, write to us at firstname.lastname@example.org.